After much ado (consisting of film studies, thumbnails, prop designs, silhouettes, perspective grids, and tears of frustration), I finally landed on what I think will pass for a composition.
Here is a rough drawing of the layout. Right now the main purpose is to check that the composition works, evokes the right emotion, and leads the eye. The drawing itself was done hastily :)
When I take it to a finish I suppose I'll work out some better designs, and spend a little more time drawing!
Lastly, I painted three different potential lighting layouts, obviously very rough. Just to get some ideas...